In the newest edition of Science Stories of EU Grants Access, Armin Curt talks about the Horizon 2020 NISCI project, a clinical trial for people with spinal cord injury.
Prof. Armin Curt of Balgrist University Hospital explains that the goal of the NISCI (Nogo Inhibition in Spinal Cord Injury) project is to find first steps for a treatment to improve functions in the patients. The clinical trial focuses on tetraplegic (quadriplegic) patients who suffer from an acute cervical injury (at the level of the neck), which results in an impairment of the legs but also of the arms and hands.
In phase 2 of the clinical trial, which is about to start, patients will be administered the antibody against Nogo-A to test its effect on nerve function and the condition of the patients, especially the hand and arm functions.
Project funded by Horizon 2020 (EU): NISCI Antibodies against Nogo-A to enhance regeneration and functional recovery after acute spinal cord injury, a multicenter European clinical proof of concept trial, 2016-2020
View interview clip here
See also Science Stories Edition 2/2018, pages 7- 10