Antagonizing the Protein Aggregation

The 10th Annual Les Turner Symposium on amyotrophic lateral sclerosis (ALS) featured presentations from leading clinicians and researchers in the field. In her presentation, Magdalini Polymendiou from the Department of Quantitative Biomedicine (UZH), presented research data from her group.

The group uncovered a novel and unexpected mechanism that counteracts pathological aggregation of proteins, which has functional consequences and potential neurotoxic effects on the brain.
Watch the full talk entitled Aggregation-dependent and independent mechanisms of toxicity in TDP-43 and FUS proteinopathies and find all details on the study published in Nature Neuroscience.