Recent publications by ZNZ members

Read here about recent papers published by members of the Neuroscience Center Zurich.

Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke.
Proc Natl Acad Sci U S A. 2019 Jun 24. pii: 201905309. doi: 10.1073/pnas.1905309116. [Epub ahead of print]
Authors: Rust R, Grönnert L, Gantner C, Enzler A, Mulders G, Weber RZ, Siewert A, Limasale YDP, Meinhardt A, Maurer MA, Sartori AM, Hofer AS, Werner C, Schwab ME.

Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system.
J Cell Biol. 2019 Jun 14
Authors: Ommer A, Figlia G, Pereira JA, Datwyler AL, Gerber J, DeGeer J, Lalli G, Suter U

Layer-specific integration of locomotion and sensory information in mouse barrel cortex.
Nat Commun. 2019 Jun 13;10(1):2585
Authors: Ayaz A, Stäuble A, Hamada M, Wulf MA, Saleem AB, Helmchen F

Consistent within-group covariance of septal and temporal hippocampal neurogenesis with behavioral phenotypes for exploration and memory retention across wild and laboratory small rodents.
Behav Brain Res. 2019 Jun 12;:112034
Authors: van Dijk RM, Wiget F, Wolfer DP, Slomianka L, Amrein I

Developing a brain atlas through deep learning
Nature Machine Intelligence. 2019 June 10. Volume 1, pages 277–287 (2019)
Authors: Asim Iqbal, Romesa Khan & Theofanis Karayannis 

Oscillatory patterns in the electroencephalogram at sleep onset.
Sleep. 2019 Jun 07
Authors: Achermann P, Rusterholz T, Stucky B, Olbrich E

Evoked response strength in primary auditory cortex predicts performance in a spectro-spatial discrimination task in rats.
J Neurosci. 2019 Jun 07
Authors: Gronskaya E, von der Behrens W

Rapid Reconfiguration of the Functional Connectome after Chemogenetic Locus Coeruleus Activation.
Neuron. 2019 Jun 07
Authors: Zerbi V, Floriou-Servou A, Markicevic M, Vermeiren Y, Sturman O, Privitera M, von Ziegler L, Ferrari KD, Weber B, De Deyn PP, Wenderoth N, Bohacek J

A chronic hypoxic response in photoreceptors alters the vitreous proteome in mice.
Exp Eye Res. 2019 Jun 07;185:107690
Authors: Schori C, Trachsel C, Grossmann J, Barben M, Klee K, Storti F, Samardzija M, Grimm C

Increased levels of midbrain immune-related transcripts in schizophrenia and in murine offspring after maternal immune activation.
Mol Psychiatry. 2019 Jun 05
Authors: Purves-Tyson TD, Weber-Stadlbauer U, Richetto J, Rothmond DA, Labouesse MA, Polesel M, Robinson K, Shannon Weickert C, Meyer U

A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology.
Sci Transl Med. 2019 Jun 5;11(495). pii: eaau6722. doi: 10.1126/scitranslmed.aau6722.
Authors: Gerez JA, Prymaczok NC, Rockenstein E, Herrmann US, Schwarz P, Adame A, Enchev RI, Courtheoux T, Boersema PJ, Riek R, Peter M, Aguzzi A, Masliah E, Picotti P

Emotional expressions associated with therapeutic inertia in multiple sclerosis care.
Mult Scler Relat Disord. 2019 Jun 04;34:17-28
Authors: Saposnik G, Oh J, Terzaghi MA, Kostyrko P, Bakdache F, Montoya A, Jaja BNR, Nisenbaum R, Ruff CC, Tobler PN

A simple sleep EEG marker in childhood predicts brain myelin 3.5 years later.
Neuroimage. 2019 Jun 03
Authors: LeBourgeois MK, Dean DC, Deoni SCL, Kohler M, Kurth S

Challenges and future perspectives in neuro-oncology
Nervenarzt. 2019 Jun;90(6):594-600. doi: 10.1007/s00115-019-0716-4.
Authors: Tabatabai G, Weller M

Where has the ‘bio’ in bio-psycho-social gone?
Curr Opin Support Palliat Care. 2019 Jun;13(2):94-98
Authors: Schweinhardt P

Broken access’ publishing corrodes quality.
Nature. 2019 Jun;570(7760):139. doi: 10.1038/d41586-019-01787-2.
Authors: Aguzzi A.

Differential expression of PKCα and -β in the zebrafish retina.
Histochem Cell Biol. 2019 Jun;151(6):521-530
Authors: Haug MF, Berger M, Gesemann M, Neuhauss SCF

Extracellular Vesicles and their miRNA Cargo: A Means of Communication between Soma and Germline in the Mammalian Reproductive System.
Chimia (Aarau). 2019 May 29;73(6):356-361
Authors: Maciel E, Mansuy IM

Scaling of brain compartments to brain size.
Neuroreport. 2019 May 22;30(8):573-579
Authors: Jäncke L, Liem F, Merillat S

Closed-Loop Acoustic Stimulation During Sleep in Children With Epilepsy: A Hypothesis-Driven Novel Approach to Interact With Spike-Wave Activity and Pilot Data Assessing Feasibility.
Front Hum Neurosci. 2019 May 21;13:166
Authors: Fattinger S, Heinzle BB, Ramantani G, Abela L, Schmitt B, Huber R

Extracellular matrix: a new player in memory maintenance and psychiatric disorders.
Swiss Med Wkly. 2019 May 20;149:w20060
Authors: Bach D, Brown SA, Kleim B, Tyagarajan S

Minimizing threat via heuristic and optimal policies recruits hippocampus and medial prefrontal cortex.
Nat Hum Behav. 2019 May 20
Authors: Korn CW, Bach DR

Alpha-blockers for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review and meta-analysis. A report from the Neuro-Urology Promotion Committee of the International Continence Society (ICS).
Neurourol Urodyn. 2019 May 16
Authors: Schneider MP, Tornic J, Sýkora R, Abo Youssef N, Mordasini L, Krhut J, Chartier-Kastler E, Davies M, Gajewski J, Schurch B, Bachmann LM, Kessler TM

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner.
Nat Commun. 2019 May 16;10(1):2192
Authors: Zurkirchen L, Varum S, Giger S, Klug A, Häusel J, Bossart R, Zemke M, Cantù C, Atak ZK, Zamboni N, Basler K, Sommer L

Width and neurophysiologic properties of tissue bridges predict recovery after cervical injury.
Neurology. 2019 May 15
Authors: Vallotton K, Huber E, Sutter R, Curt A, Hupp M, Freund P

High-density multi-fiber photometry for studying large-scale brain circuit dynamics.
Nat Methods. 2019 May 13
Authors: Sych Y, Chernysheva M, Sumanovski LT, Helmchen F

How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch.
Neuron. 2019 May 10. pii: S0896-6273(19)30379-4. doi: 10.1016/j.neuron.2019.04.022.
Authors: Pagani M, Albisetti GW, Sivakumar N, Wildner H, Santello M, Johannssen HC, Zeilhofer HU.

The Tilted Self: Visuo-Graviceptive Mismatch in the Full-Body Illusion.
Front Neurol. 2019 May 08;10:436
Authors: Thür C, Roel Lesur M, Bockisch CJ, Lopez C, Lenggenhager B

The Influence of Cochlear Implantation on Tinnitus in Patients with Single-Sided Deafness: A Systematic Review.
Otolaryngol Head Neck Surg. 2019 May 07;194599819846084
Authors: Peter N, Liyanage N, Pfiffner F, Huber A, Kleinjung T

Deep Survey of GABAergic Interneurons: Emerging Insights From Gene-Isoform Transcriptomics.
Front Mol Neurosci. 2019 May 07;12:115
Authors: Que L, Winterer J, Földy C

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes.
Elife. 2019 May 07;8:
Authors: Dimas P, Montani L, Pereira JA, Moreno D, Trötzmüller M, Gerber J, Semenkovich CF, Köfeler HC, Suter U

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs.
Proc Natl Acad Sci U S A. 2019 May 06
Authors: Sarker G, Sun W, Rosenkranz D, Pelczar P, Opitz L, Efthymiou V, Wolfrum C, Peleg-Raibstein D

Checking macrophages at the border.
Nat Neurosci. 2019 May 06
Authors: Utz SG, Greter M

Frequency, Characteristics and Risk Factors of Aggressive Incidents in a Paediatric Rehabilitation Setting: A Prospective Survey.
Dev Neurorehabil. 2019 May 06;:1-9
Authors: Meier SBB, Uenver Y, Stooss A, Meyer-Heim A

Branch-restricted localization of phosphatase Prl-1 specifies axonal synaptogenesis domains.
Science. 2019 May 03;364(6439):
Authors: Urwyler O, Izadifar A, Vandenbogaerde S, Sachse S, Misbaer A, Schmucker D

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.
Immunity. 2019 May 02
Authors: Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, Waisman A, Opitz L, Oukka M, Schreiner B, Pelczar P, Becher B

Local sleep-like events during wakefulness and their relationship to decreased alertness in astronauts on ISS.
NPJ Microgravity. 2019 May 02;5:10Authors: Petit G, Cebolla AM, Fattinger S,
Petieau M, Summerer L, Cheron G, Huber R

A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites.
Biol Chem. 2019 May 01
Authors: Konietzko U, Gersbacher MT, Streuli J, Krüger M, Thöni S, Kins S, Nitsch RM

Left temporal plane growth predicts language development in newborns with congenital heart disease.
Brain. 2019 May 01;142(5):1270-1281
Authors: Jakab A, Meuwly E, Feldmann M, Rhein MV, Kottke R, O’Gorman Tuura R, Latal B, Knirsch W, Research Group Heart and Brain

Slow-wave sleep and motor progression in Parkinson disease.
Ann Neurol. 2019 May;85(5):765-770
Authors: Schreiner SJ, Imbach LL, Werth E, Poryazova R, Baumann-Vogel H, Valko PO, Murer T, Noain D, Baumann CR

High frequency oscillations as markers of epileptogenic tissue – End of the party?
Clin Neurophysiol. 2019 May;130(5):624-626
Authors: Fedele T, Ramantani G, Sarnthein J

Repetitive ocular vestibular evoked myogenic potential stimulation for the diagnosis of myasthenia gravis: Optimization of stimulation parameters.
Clin Neurophysiol. 2019 Apr 25;130(7):1125-1134
Authors: Wirth MA, Valko Y, Rosengren SM, Schmückle-Meier T, Bockisch CJ, Straumann D, Landau K, Weber KP

Pavlovian-to-instrumental transfer after human threat conditioning.
Learn Mem. 2019 Apr 19;26(5):167-175
Authors: Xia Y, Gurkina A, Bach DR

Beneficial effects of Silexan on sleep are mediated by its anxiolytic effect.
J Psychiatr Res. 2019 Apr 17;115:69-74
Authors: Seifritz E, Schläfke S, Holsboer-Trachsler E

Tocilizumab treatment in severe recurrent anti-MOG-associated optic neuritis.
Neurology. 2019 Apr 16;92(16):765-767
Authors: Hayward-Koennecke H, Reindl M, Martin R, Schippling S

Suggested guidelines for the diagnosis and management of urea cycle disorders: First revision.
J Inherit Metab Dis. 2019 Apr 14
Authors: Häberle J, Burlina A, Chakrapani A, Dixon M, Karall D, Lindner M, Mandel H, Martinelli D, Pintos-Morell G, Santer R, Skouma A, Servais A, Tal G, Rubio V, Huemer M, Dionisi-Vici C

Diurnal changes in human brain glutamate + glutamine levels in the course of development and their relationship to sleep.
Neuroimage. 2019 Apr 13;196:269-275
Authors: Volk C, Jaramillo V, Studler M, Furrer M, O’Gorman Tuura RL, Huber R

Immunotherapy for neurodegeneration?
Science. 2019 Apr 12;364(6436):130-131. doi: 10.1126/science.aaw0685.
Authors: Liu Y, Aguzzi A.

Shared neural mechanisms between imagined and perceived egocentric motion – A combined GVS and fMRI study.
Cortex. 2019 Apr 12;119:20-32
Authors: Macauda G, Moisa M, Mast FW, Ruff CC, Michels L, Lenggenhager B

An in vivo wound healing model for the characterization of the angiogenic process and its modulation by pharmacological interventions.
Sci Rep. 2019 Apr 12;9(1):6004
Authors: Schneider MK, Ioanas HI, Xandry J, Rudin M

Smart Toolkit for Fluorescence Tomography: simulation, reconstruction, and validation.
IEEE Trans Biomed Eng. 2019 Apr 11
Authors: Ren W, Isler H, Wolf M, Ripoll J, Rudin M

Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4+ T Cells in Multiple Sclerosis.
Front Immunol. 2019 Apr 10;10:540
Authors: Faigle W, Cruciani C, Wolski W, Roschitzki B, Puthenparampil M, Tomas-Ojer P, Sellés-Moreno C, Zeis T, Jelcic I, Schaeren-Wiemers N, Sospedra M, Martin R

Absolute and relative pitch processing in the human brain: neural and behavioral evidence.
Brain Struct Funct. 2019 Apr 09
Authors: Leipold S, Brauchli C, Greber M, Jäncke L

The spinal transcriptome after cortical stroke – In search of molecular factors regulating spontaneous recovery in the spinal cord.
J Neurosci. 2019 Apr 08
Authors: Kaiser J, Maibach M, Salpeter I, Hagenbuch N, Souza VBC, Robinson MD, Schwab ME

Neurophysiological signature of gamma-hydroxybutyrate augmented sleep in male healthy volunteers may reflect biomimetic sleep enhancement: a randomized controlled trial.
Neuropsychopharmacology. 2019 Apr 08
Authors: Dornbierer DA, Baur DM, Stucky B, Quednow BB, Kraemer T, Seifritz E, Bosch OG, Landolt HP

Psilocybin-assisted mindfulness training modulates self-consciousness and brain default mode network connectivity with lasting effects.
Neuroimage. 2019 Apr 06;196:207-215
Authors: Smigielski L, Scheidegger M, Kometer M, Vollenweider FX

Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation.
Commun Biol. 2019 Apr 05;2:127
Authors: Romanos J, Benke D, Saab AS, Zeilhofer HU, Santello M

Improvement of Emotional Empathy and Cluster B Personality Disorder Symptoms Associated With Decreased Cocaine Use Severity.
Front Psychiatry. 2019 Apr 05;10:213
Authors: Vonmoos M, Eisenegger C, Bosch OG, Preller KH, Hulka LM, Baumgartner M, Seifritz E, Quednow BB

Endogenous amylin contributes to the birth of microglial cells in the arcuate nucleus of the hypothalamus and the area postrema during fetal development.
Am J Physiol Regul Integr Comp Physiol. 2019 Apr 03
Authors: Lutz TA, Le Foll C

Actimetry in infant sleep research: an approach to facilitate comparability.
Sleep. 2019 Apr 03
Authors: Schoch SF, Jenni OG, Kohler M, Kurth S

Artificial intelligence for understanding concussion: Retrospective cluster analysis on the balance and vestibular diagnostic data of concussion patients.
PLoS One. 2019 Apr 02;14(4):e0214525
Authors: Visscher RMS, Feddermann-Demont N, Romano F, Straumann D, Bertolini G

Ossified blood vessels in primary familial brain calcification elicit a neurotoxic astrocyte response.
Brain. 2019 Apr 1;142(4):885-902. doi: 10.1093/brain/awz032.
Zarb Y, Weber-Stadlbauer U, Kirschenbaum D, Kindler DR, Richetto J, Keller D, Rademakers R, Dickson DW, Pasch A, Byzova T, Nahar K, Voigt FF, Helmchen F, Boss A, Aguzzi A, Klohs J, Keller A

SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease.
J Exp Med. 2019 Apr 1;216(4):743-756. doi: 10.1084/jem.20171885. Epub 2019 Mar 6.
Authors: Zhu C, Li B, Frontzek K, Liu Y, Aguzzi A

Higher levels of motor competence are associated with reduced interference in action perception across the lifespan.
Psychol Res. 2019 Apr;83(3):432-444
Authors: Wermelinger S, Gampe A, Daum MM

Association study and a systematic meta-analysis of the VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder.
J Neural Transm (Vienna). 2019 Apr;126(4):517-529
Authors: Grünblatt E, Werling AM, Roth A, Romanos M, Walitza S

Changes of Electrocochleographic Responses During Cochlear Implantation Presented at the Annual Meeting of ADANO 2016 in Berlin.
Otol Neurotol. 2019 Apr;40(4):e424-e429
Authors: Dalbert A, Pfiffner F, Hoesli M, Meerwein C, Veraguth D, Roosli C, Huber A

Automated registration of magnetic resonance imaging and optoacoustic tomography data for experimental studies.
Neurophotonics. 2019 Apr;6(2):025001
Authors: Ren W, Skulason H, Schlegel F, Rudin M, Klohs J, Ni R

The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation.
Mol Brain. 2019 Mar 29;12(1):27
Authors: Tackenberg C, Nitsch RM

Reinstating verbal memories with virtual contexts: Myth or reality?
PLoS One. 2019 Mar 29;14(3):e0214540
Authors: Wälti MJ, Woolley DG, Wenderoth N

True to which self? Lay rationalism and decision satisfaction in self-control conflicts.
J Pers Soc Psychol. 2019 Mar 28
Authors: Kokkoris MD, Hoelzl E, Alós-Ferrer C

Persistent hippocampal neural firing and hippocampal-cortical coupling predict verbal working memory load.
Sci Adv. 2019 Mar 27;5(3):eaav3687
Authors: Boran E, Fedele T, Klaver P, Hilfiker P, Stieglitz L, Grunwald T, Sarnthein J

Investigating the Efficacy of an Individualized Alpha/Delta Neurofeedback Protocol in the Treatment of Chronic Tinnitus.
Neural Plast. 2019 Mar 26;2019:3540898
Authors: Güntensperger D, Thüring C, Kleinjung T, Neff P, Meyer M

Anti-Nogo-A antibodies as a potential causal therapy for lower urinary tract dysfunction after spinal cord injury.
J Neurosci. 2019 Mar 22
Authors: Schneider MP, Sartori AM, Ineichen BV, Moors S, Engmann AK, Hofer AS, Weinmann O, Kessler TM, Schwab ME

Hierarchical Prediction Errors in Midbrain and Basal Forebrain during Sensory Learning.
Neuron. 2019 Mar 20;101(6):1196-1201
Authors: Iglesias S, Mathys C, Brodersen KH, Kasper L, Piccirelli M, den Ouden HEM, Stephan KE

Editorial Note to: Hierarchical Prediction Errors in Midbrain and Basal Forebrain during Sensory Learning.
Neuron. 2019 Mar 20;101(6):1195
Authors: Iglesias S, Mathys C, Brodersen KH, Kasper L, Piccirelli M, den Ouden HEM, Stephan KE

Neurostimulation Reveals Context-Dependent Arbitration Between Model-Based and Model-Free Reinforcement Learning.
Cereb Cortex. 2019 Mar 19
Authors: Weissengruber S, Lee SW, O’Doherty JP, Ruff CC

Magnetometer-Based Drift Correction During Rest inIMU Arm Motion Tracking.
Sensors (Basel). 2019 Mar 15;19(6):
Authors: Wittmann F, Lambercy O, Gassert R

Psychobiological Factors of Sexual Functioning in Aging Women – Findings From the Women 40+ Healthy Aging Study.
Front Psychol. 2019 Mar 13;10:546
Authors: Mernone L, Fiacco S, Ehlert U

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
Elife. 2019 Mar 13;8:
Authors: Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde-Visser S, Samardzija M, Meneau I, Barben M, Karademir D, Pauzuolyte V, Boye SL, Blaser F, Ullmer C, Dunaief JL, Hornemann T, Rohrer L, den Hollander AI, von Eckardstein A, Fingerle J, Maugeais C, Grimm C

Immunotherapy for glioblastoma: quo vadis?
Nat Rev Clin Oncol. 2019 Mar 13
Authors: Weller M, Le Rhun E

Altering brain dynamics with transcranial random noise stimulation.
Sci Rep. 2019 Mar 11;9(1):4029. doi: 10.1038/s41598-019-40335-w.
Authors: van der Groen O, Mattingley JB, Wenderoth N

GABA and glutamate moderate beta-amyloid related functional connectivity in cognitively unimpaired old-aged adults.
Neuroimage Clin. 2019;22:101776. doi: 10.1016/j.nicl.2019.101776. Epub 2019 Mar 12.
Authors: Quevenco FC, Schreiner SJ, Preti MG, van Bergen JMG, Kirchner T, Wyss M, Steininger SC, Gietl A, Leh SE, Buch A, Pruessmann KP, Hock C, Nitsch RM, Henning A, Van De Ville D, Unschuld PG

Elucidation of the phenotypic spectrum and genetic landscape in primary and secondary microcephaly.
Genet Med. 2019 Mar 07
Authors: Boonsawat P, Joset P, Steindl K, Oneda B, Gogoll L, Azzarello-Burri S, Sheth F, Datar C, Verma IC, Puri RD, Zollino M, Bachmann-Gagescu R, Niedrist D, Papik M, Figueiro-Silva J, Masood R, Zweier M, Kraemer D, Lincoln S, Rodan L, Undiagnosed Diseases Network (UDN), Passemard S, Drunat S, Verloes A, Horn AHC, Sticht H, Steinfeld R, Plecko B, Latal B, Jenni O, Asadollahi R, Rauch A

Altered limbic and autonomic processing supports brain-heart axis in Takotsubo syndrome.
Eur Heart J. 2019 Mar 05
Authors: Templin C, Hänggi J, Klein C, Topka MS, Hiestand T, Levinson RA, Jurisic S, Lüscher TF, Ghadri JR, Jäncke L

Spinal GABAA receptors for pain control: back to the future?
Br J Anaesth. 2019 Mar 04
Authors: Zeilhofer HU, Neumann E, Munro G

A Revised View on Growth and Remodeling in the Retinal Vasculature.
Sci Rep. 2019 Mar 01;9(1):3263
Authors: Rust R, Grönnert L, Dogançay B, Schwab ME

Positron emission tomography of type 2 cannabinoid receptors for detecting inflammation in the central nervous system.
Acta Pharmacol Sin. 2019 Mar;40(3):351-357
Authors: Ni R, Mu L, Ametamey S